LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP000829

UniProt Annotations

Entry Information
Gene Nameapolipoprotein F
Protein EntryAPOF_HUMAN
UniProt IDQ13790
SpeciesHuman
Comments
Comment typeDescription
CautionIt is uncertain whether Met-1 or Met-12 is the initiator.
FunctionMinor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.
PtmO-glycosylated with core 1 or possibly core 8 glycans.
Subcellular LocationSecreted.
Tissue SpecificityExpressed by the liver and secreted in plasma.