LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP002069

Record overview

LMPD IDLMP002069
Gene ID8396
SpeciesHomo sapiens (Human)
Gene Namephosphatidylinositol-5-phosphate 4-kinase, type II, beta
Gene SymbolPIP4K2B
SynonymsPI5P4KB; PIP5K2B; PIP5KIIB; PIP5KIIbeta
Alternate namesphosphatidylinositol 5-phosphate 4-kinase type-2 beta; PIP4KII-beta; PTDINS(4)P-5-kinase; PI(5)P 4-kinase type II beta; diphosphoinositide kinase 2-beta; ptdIns(5)P-4-kinase isoform 2-beta; 1-phosphatidylinositol-4-phosphate kinase; 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; 1-phosphatidylinositol-5-phosphate 4-kinase 2-beta; phosphatidylinositol-5-phosphate 4-kinase type-2 beta; phosphatidylinositol 5-phosphate 4-kinase type II beta; phosphatidylinositol-4-phosphate 5-kinase, type II, beta
Chromosome17
Map Location17q12
EC Number2.7.1.149
SummaryThe protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PIP4K2B

Proteins

phosphatidylinositol 5-phosphate 4-kinase type-2 beta
Refseq ID:NP_003550
Protein GI:4505819
UniProt ID:P78356
mRNA ID:NM_003559
Length:416
RefSeq Status:REVIEWED
MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCP
MVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVV
TRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEE
RAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNP
EQYSKRFNEFMSNILT