LIPID MAPS® Gene/Proteome Database (LMPD)

Introduction | Overview of Interfaces | Browse | Search | Download

LMPD Record

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP006723

UniProt Annotations

Entry Information
Gene Nameacyl-CoA synthetase medium-chain family member 5
Protein EntryACSM5_HUMAN
UniProt IDQ6NUN0
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q6NUN0-1; Sequence=Displayed; Name=2; IsoId=Q6NUN0-2; Sequence=VSP_028398; Note=No experimental confirmation available.;
Catalytic ActivityATP + a carboxylate + CoA = AMP + diphosphate + an acyl-CoA.
CofactorName=Mg(2+); Xref=ChEBI
FunctionHas medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) (By similarity).
Sequence CautionSequence=BAA91273.1; Type=Frameshift; Positions=560; Evidence= ;
SimilarityBelongs to the ATP-dependent AMP-binding enzyme family.
Subcellular LocationMitochondrion matrix .
Tissue SpecificityDetected in kidney and liver.