LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP006754

UniProt Annotations

Entry Information
Gene Nameacyl-CoA synthetase medium-chain family member 4
Protein EntryACSM4_HUMAN
UniProt IDP0C7M7
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityATP + a carboxylate + CoA = AMP + diphosphate + an acyl-CoA.
CofactorName=Mg(2+); Xref=ChEBI
FunctionHas medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) (By similarity).
SimilarityBelongs to the ATP-dependent AMP-binding enzyme family.
Subcellular LocationMitochondrion matrix .