LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP007288

UniProt Annotations

Entry Information
Gene NameGic2p
Protein EntryGIC2_YEAST
UniProt IDQ06648
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionRequired for cell size and shape control, bud site selection, bud emergence, actin cytoskeletal organization, mitotic spindle orientation/positioning, and mating projection formation in response to mating pheromone.
InteractionP32458:CDC11; NbExp=2; IntAct=EBI-7585, EBI-4178; P32468:CDC12; NbExp=5; IntAct=EBI-7585, EBI-4182; P32457:CDC3; NbExp=3; IntAct=EBI-7585, EBI-4429;
MiscellaneousPresent with 1130 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the BORG/CEP family. {ECO:0000305}.
SimilarityContains 1 CRIB domain. {ECO:0000255|PROSITE- ProRule:PRU00057}.
Subcellular LocationBud neck {ECO:0000250}. Bud tip {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
SubunitInteracts with GTP-bound CDC42.