LIPID MAPS® Gene/Proteome Database (LMPD)

Introduction | Overview of Interfaces | Browse | Search | Download

LMPD Record

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP007339

UniProt Annotations

Entry Information
Gene NameYpi1p
Protein EntryYPI1_YEAST
UniProt IDP43587
SpeciesYeast (S288c)
Comments
Comment typeDescription
CautionWas originally (PubMed:14506263) thought to be an inhibitor of type 1 phosphatases using in vitro experiments, but further in vivo experiments (PubMed:18172024) showed that it was rather an activator of these phosphatases
CautionWas originally (PubMed:14506263) thought to be an inhibitor of type 1 phosphatases using in vitro experiments, but further in vivo experiments (PubMed:18172024) showed that it was rather an activator of these phosphatases. {ECO:0000305|PubMed:14506263, ECO:0000305|PubMed:18172024}.
FunctionRegulator of type 1 phosphatases which maintains protein phosphatase activity under strict control. Regulates the nuclear localization of type 1 phosphatase GLC7 and SDS22, and is involved in the regulation of mRNA 3'-end processing. May also regulate the activity of type 1 phosphatase PPZ1. {ECO:0000269|PubMed:14506263, ECO:0000269|PubMed:16137619, ECO:0000269|PubMed:17142459, ECO:0000269|PubMed:18172024}.
InteractionP32598:GLC7; NbExp=4; IntAct=EBI-22913, EBI-13715; P36047:SDS22; NbExp=4; IntAct=EBI-22913, EBI-16783;
MiscellaneousPresent with 1080 molecules/cell in log phase SD medium
MiscellaneousPresent with 1080 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the YPI1 family
SimilarityBelongs to the YPI1 family. {ECO:0000305}.
Subcellular LocationNucleus {ECO:0000269|PubMed:17142459, ECO:0000269|PubMed:18172024}.
SubunitInteracts with GLC7, PPZ1 and SDS22. {ECO:0000269|PubMed:14506263, ECO:0000269|PubMed:17142459, ECO:0000269|PubMed:18172024}.