LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP007439

UniProt Annotations

Entry Information
Gene NameSte5p
Protein EntrySTE5_YEAST
UniProt IDP32917
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionComponent of the pheromone signal transduction pathway. It mediates pheromone signals acting between STE20 and STE11. It is absolutely required for pheromone-induced transcription of FUS1. May play a role in cell-cycle arrest in response to pheromone.
InteractionQ6FPF2:CAGL0J04290g (xeno); NbExp=2; IntAct=EBI-18373, EBI-8783845; Q5A1D3:CEK1 (xeno); NbExp=2; IntAct=EBI-18373, EBI-8783371; Q5A281:CEK2 (xeno); NbExp=2; IntAct=EBI-18373, EBI-8785242; P11710:FUS1; NbExp=2; IntAct=EBI-18373, EBI-7179; P16892:FUS3; NbExp=10; IntAct=EBI-18373, EBI-7193; Q6CNR3:KLLA0E10539g (xeno); NbExp=2; IntAct=EBI-18373, EBI-8785667; C8V7D1:mpkB (xeno); NbExp=2; IntAct=EBI-18373, EBI-8783425; P23561:STE11; NbExp=7; IntAct=EBI-18373, EBI-18259; P18851:STE4; NbExp=2; IntAct=EBI-18373, EBI-7390; P06784:STE7; NbExp=8; IntAct=EBI-18373, EBI-18389;
MiscellaneousPresent with 1900 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PtmMay be regulated at the phosphorylation level, and by the mating type of the cell and depends on an intact pheromone- response pathway. {ECO:0000269|PubMed:17330950}.
SimilarityTo yeast FAR1. {ECO:0000305}.
Subcellular LocationCytoplasm.