LIPID MAPSĀ® Gene/Proteome Database (LMPD)

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LMPD Record

LMP007677

UniProt Annotations

Entry Information
Gene Namelipid A phosphoethanolamine transferase
Protein EntryEPTA_ECOLI
UniProt IDP30845
SpeciesE. coli
Comments
Comment typeDescription
FunctionCatalyzes the addition of a phosphoethanolamine moiety to the lipid A. The phosphoethanolamine modification is required for resistance to polymyxin (By similarity). {ECO:0000250}.
InductionThe eptA-basRS operon is positively autoregulated by BasR under high iron or aluminum concentration conditions. {ECO:0000250}.
Sequence CautionSequence=AAA97013.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
SimilarityBelongs to the phosphoethanolamine transferase family. EptA subfamily. {ECO:0000305}.
Subcellular LocationCell inner membrane {ECO:0000269|PubMed:16079137}; Multi-pass membrane protein {ECO:0000269|PubMed:16079137}.
SubunitHas been isolated as a 91 kDa complex containing ZipA- EptA and an unidentified 24 kDa protein. {ECO:0000269|PubMed:16079137}.