LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP007748

UniProt Annotations

Entry Information
Gene Namecyclopropane fatty acyl phospholipid synthase, SAM-dependent
Protein EntryCFA_ECOLI
UniProt IDP0A9H7
SpeciesE. coli
Comments
Comment typeDescription
Catalytic ActivityS-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
Enzyme RegulationInhibited by sinefungin, A9145C and S-adenosyl- L-homocysteine. {ECO:0000269|PubMed:1445840}.
FunctionTransfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge. {ECO:0000250}.
InteractionP37024:hrpB; NbExp=1; IntAct=EBI-1124838, EBI-549226;
PathwayLipid metabolism; fatty acid biosynthesis.
SimilarityBelongs to the CFA/CMAS family. {ECO:0000305}.
Subcellular LocationCytoplasm.