LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP007869

UniProt Annotations

Entry Information
Gene NameProtein ELO-6
Protein EntryELO6_CAEEL
UniProt IDQ20303
SpeciesC. elegans
Comments
Comment typeDescription
Catalytic ActivityA very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2). {ECO:0000269|PubMed:15340492}.
FunctionCondensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs) and monomethyl branched-chain fatty acids (mmBCFAs). Required for the formation of isoheptadecanoate (C17iso). {ECO:0000269|PubMed:15340492}.
PathwayLipid metabolism; fatty acid biosynthesis. {ECO:0000269|PubMed:15340492}.
SimilarityBelongs to the ELO family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue SpecificityExpressed in the gut, neurons, pharynx and muscles of the vulva. {ECO:0000269|PubMed:15340492}.