LIPID MAPSĀ® Gene/Proteome Database (LMPD)

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LMPD Record

LMP008174

UniProt Annotations

Entry Information
Gene NameProtein GGTB-1
Protein EntryGGTB2_CAEEL
UniProt IDP41992
SpeciesC. elegans
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=a; IsoId=P41992-1; Sequence=Displayed; Note=No experimental confirmation available.; Name=b; IsoId=P41992-2; Sequence=VSP_018160; Note=No experimental confirmation available.;
Catalytic ActivityGeranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate.
CofactorName=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; Note=Binds 1 zinc ion per subunit. {ECO:0000250};
FunctionCatalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal. {ECO:0000250}.
SimilarityBelongs to the protein prenyltransferase subunit beta family. {ECO:0000305}.
SimilarityContains 5 PFTB repeats. {ECO:0000305}.
SubunitHeterodimer of an alpha and a beta subunit. {ECO:0000250}.