LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP010082

UniProt Annotations

Entry Information
Gene Namecytochrome P450, family 86, subfamily A, polypeptide 4
Protein EntryC86A4_ARATH
UniProt IDQ9LMM1
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityRH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.
CofactorName=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
Disruption PhenotypeNo visible phenotype under normal growth conditions, but mutant plants have reduced content of the flower polyesters 16-hydroxypalmitate, 10,16-dihydroxypalmitate and 1,16- hexadecanedioate. {ECO:0000269|PubMed:19959665}.
FunctionCatalyzes the omega-hydroxylation of various fatty acids (FA). Acts on saturated and unsaturated fatty acids with chain lengths from C12 to C18. Involved in the biosynthesis of 16- hydroxypalmitate. {ECO:0000269|PubMed:15709153, ECO:0000269|PubMed:17427946, ECO:0000269|PubMed:19959665}.
InductionBy abscisic acid (ABA), auxin, the etylene precursor ACC and cold treatment. Down-regulated by wounding and in etiolated seedlings. {ECO:0000269|PubMed:15709153}.
SimilarityBelongs to the cytochrome P450 family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue SpecificityExpressed in stems, flowers and siliques. {ECO:0000269|PubMed:15709153}.