LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP010084

UniProt Annotations

Entry Information
Gene Namecytochrome P450, family 86, subfamily A, polypeptide 8
Protein EntryC86A8_ARATH
UniProt IDO80823
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityRH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.
CofactorName=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
Disruption PhenotypeOrgan fusion between rosette leaves and in inflorescences. {ECO:0000269|PubMed:11493698}.
FunctionCatalyzes the omega-hydroxylation of various fatty acids (FA). Acts on saturated and unsaturated fatty acids with chain lengths from C12 to C18. May be involved in the biosynthesis of cutin in the epidermis which prevents post-genital organ fusions. Hydroxylated FAs may be important for trichome differentiation, establishment of apical dominance and senescence. {ECO:0000269|PubMed:11493698, ECO:0000269|PubMed:15709153, ECO:0000269|PubMed:17427946}.
InductionInduced by abscisic acid (ABA) and auxin. Down- regulated by wounding. {ECO:0000269|PubMed:15709153}.
SimilarityBelongs to the cytochrome P450 family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue SpecificityExpressed in leaves, stems, flowers and siliques. Expressed at low levels in roots. {ECO:0000269|PubMed:15709153}.