LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP010220

UniProt Annotations

Entry Information
Gene Namefatty acyl-CoA reductase CER4
Protein EntryFACR3_ARATH
UniProt IDQ93ZB9
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityHexadecanal + CoA + NADP(+) = hexadecanoyl-CoA + NADPH.
Disruption PhenotypeGlossy stem wax. Major decreases in primary alcohols and wax esters, and slightly elevated levels of aldehydes, alkanes, secondary alcohols, and ketones. {ECO:0000269|PubMed:12228482, ECO:0000269|PubMed:16980563, ECO:0000269|PubMed:18470011}.
FunctionCatalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C24:0 and C26:0. May be unable to use saturated and monounsaturated C16 and C18 acyl-CoA as substrates. Involved in cuticular wax formation. {ECO:0000269|PubMed:16980563, ECO:0000269|PubMed:19062129}.
Sequence CautionSequence=CAA20592.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAB80096.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the fatty acyl-CoA reductase family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum {ECO:0000305|PubMed:16980563}.
Tissue SpecificityExpressed in leaves, stems, flowers, siliques and roots. Detected in epidermal cells of leaves and stems, in trichomes and in the elongation zone of young roots. {ECO:0000269|PubMed:16980563}.