LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP010976

UniProt Annotations

Entry Information
Gene Nameprobable E3 ubiquitin ligase SUD1
Protein EntrySUD1_ARATH
UniProt IDF4JKK0
SpeciesArabidopsis
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=F4JKK0-1; Sequence=Displayed; Name=2; IsoId=F4JKK0-2; Sequence=VSP_046615; Note=Derived from EST data.;
Developmental StageConstitutively expressed throughout development. {ECO:0000269|PubMed:22635115}.
Disruption PhenotypeSemiglossy stem. Elevated drought tolerance and reduced transpiration rate. Elevated amounts of 18-carbon- length cutin monomers and shift in the cuticular wax profile toward the very-long-chain free fatty acids tetracosanoic acid (C24) and hexacosanoic acid (C26). {ECO:0000269|PubMed:22635115}.
DomainThe RING-CH-type zinc finger domain is required for E3 ligase activity. {ECO:0000255|PROSITE-ProRule:PRU00623}.
FunctionProbable E3 ubiquitin ligase acting as a positive post- transcriptional regulator of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity. Might be involved in the quality control that degrades misfolded proteins (By similarity). {ECO:0000250}.
PathwayProtein modification; protein ubiquitination.
Sequence CautionSequence=CAA17562.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAB80127.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityContains 1 RING-CH-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00623}.
Subcellular LocationMembrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue SpecificityExpressed in cotyledons, leaves, roots, stems, inflorescences and siliques. Expression higher at the top than at the base of the stem. {ECO:0000269|PubMed:22635115}.