LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP011090

UniProt Annotations

Entry Information
Gene Namefatty acid elongation machinery component ECERIFERUM2
Protein EntryCER2_ARATH
UniProt IDQ39048
SpeciesArabidopsis
Comments
Comment typeDescription
Disruption PhenotypeBright green and glossy stems and siliques due to low abundance of cuticular wax. Increased levels of C26 and C28 alcohols and disappearance of C29 alkane and C30 alcohol in the stem wax. {ECO:0000269|PubMed:17376164, ECO:0000269|PubMed:8820603, ECO:0000269|PubMed:9390429}.
FunctionInvolved in biosynthesis of the epicuticular wax. Plays a role in very-long-chain fatty acid (VLCFA) biosynthesis and is required for C28 fatty acid elongation in stem. Despite its classification as a BAHD acyltransferase based on sequence homology, CER2 does not seem to share the catalytic mechanism of the members of the BAHD family. {ECO:0000269|PubMed:17376164, ECO:0000269|PubMed:22930748, ECO:0000269|PubMed:23384041}.
SimilarityBelongs to the plant acyltransferase family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum. Nucleus {ECO:0000305}.
Tissue SpecificityExpressed at high levels in the epidermis of stems and young siliques. Expressed in flowers. {ECO:0000269|PubMed:23384041, ECO:0000269|PubMed:8820603}.