LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP011091

UniProt Annotations

Entry Information
Gene Nameprotein ECERIFERUM 1
Protein EntryCER1_ARATH
UniProt IDF4HVY0
SpeciesArabidopsis
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=F4HVY0-1; Sequence=Displayed; Name=2; IsoId=F4HVY0-2; Sequence=VSP_044264; Note=Derived from EST data. No experimental confirmation available.; Name=3; IsoId=F4HVY0-3; Sequence=VSP_044263; Note=No experimental confirmation available.;
Disruption PhenotypeGlossy stem and fruit and reduced fertility due to the inability of the pollen grains to rehydrate on the stigma surface. Disappearance of the wax crystals. Decreased C29, C31 and C33 alkane contents. Increased susceptibility to soil water deficit. {ECO:0000269|PubMed:21386033, ECO:0000269|PubMed:8718622}.
FunctionAldehyde decarbonylase involved in the conversion of aldehydes to alkanes. Core component of a very-long-chain alkane synthesis complex. Involved in epicuticular wax biosynthesis and pollen fertility. {ECO:0000269|PubMed:21386033, ECO:0000269|PubMed:22773744, ECO:0000269|PubMed:8718622}.
InductionDown regulated by cold and dark stresses. Up-regulated by low humidity, osmotic stress and abscisic acid treatment. No effet of methyl jasmonate, GA3, salicylic acid, cytokinin or auxin treatments. {ECO:0000269|PubMed:19819982, ECO:0000269|PubMed:21386033}.
Sequence CautionSequence=AAC24374.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAA11024.1; Type=Erroneous termination; Positions=588; Note=Translated as Leu.; Evidence={ECO:0000305}; Sequence=BAA11024.1; Type=Frameshift; Positions=560; Evidence={ECO:0000305};
SimilarityBelongs to the sterol desaturase family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000269|PubMed:19892830, ECO:0000269|PubMed:22773744}; Multi- pass membrane protein {ECO:0000269|PubMed:19892830, ECO:0000269|PubMed:22773744}.
SubunitHomodimer. Interacts with CER3, CYTB5-B, CYTB5-C, CYTB5-D and CYTB5-E. {ECO:0000269|PubMed:22773744}.
Tissue SpecificityExpressed in seedlings, stems, leaves, flowers, fruits and siliques. Not detected in roots, pollen and seeds. Expressed in trichomes, cotyledons, shoot apical meristem and leaf primordia. Preferentially associated with young leaves rather than mature leaves. Expressed in the epidermis of the stem and caulines leaves, in the carpels and the sepals. {ECO:0000269|PubMed:21386033, ECO:0000269|PubMed:8718622}.