LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP011738

UniProt Annotations

Entry Information
Gene Namealkylglycerol monooxygenase
Protein EntryALKMO_DANRE
UniProt IDQ6NYE4
SpeciesZebrafish
Comments
Comment typeDescription
Catalytic Activity1-alkyl-sn-glycerol + tetrahydrobiopterin + O(2) = 1-O-alkyl-sn-glycerol + dihydrobiopterin + H(2)O.
CofactorName=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000250};
FunctionGlyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes (By similarity). {ECO:0000250}.
SimilarityBelongs to the sterol desaturase family. TMEM195 subfamily. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.