LIPID MAPS® Gene/Proteome Database (LMPD)

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LMP012374

Record overview

LMPD IDLMP012374
Gene ID392636
SpeciesHomo sapiens (Human)
Gene Namealkylglycerol monooxygenase
Gene SymbolAGMO
SynonymsTMEM195;
Chromosome7
Map Location7p21.2
SummaryThe protein encoded by this gene is a tetrahydrobiopterin- and iron-dependent enzyme that cleaves the ether bond of alkylglycerols. Sequence comparisons distinguish this protein as forming a third, distinct class of tetrahydrobiopterin-dependent enzymes. Variations in this gene have been associated with decreased glucose-stimulated insulin response, type 2 diabetes, and susceptibility to intracranial aneurysms. [provided by RefSeq, Aug 2012]
OrthologsView orthologs and multiple alignments for AGMO

Proteins

alkylglycerol monooxygenase
Refseq ID:NP_001004320
Protein GI:51972212
UniProt ID:X5D773
mRNA ID:NM_001004320
Length:445
RefSeq Status:
MKNPEAQQDVSVSQGFRMLFYTMKPSETSFQTLEEVPDYVKKATPFFISLMLLELVVSWILKGKPPGRLDDALTSISAGVLSRLPSLFFRSIELTSYIYI
WENYRLFNLPWDSPWTWYSAFLGVDFGYYWFHRMAHEVNIMWAGHQTHHSSEDYNLSTALRQSVLQIYTSWIFYSPLALFIPPSVYAVHLQFNLLYQFWI
HTEVINNLGPLELILNTPSHHRVHHGRNRYCIDKNYAGVLIIWDKIFGTFEAENEKVVYGLTHPINTFEPIKVQFHHLFSIWTTFWATPGFFNKFSVIFK
GPGWGPGKPRLGLSEEIPEVTGKEVPFSSSSSQLLKIYTVVQFALMLAFYEETFADTAALSQVTLLLRVCFIILTLTSIGFLLDQRPKAAIMETLRCLMF
LMLYRFGHLKPLVPSLSSAFEIVFSICIAFWGVRSMKQLTSHPWK