LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP012425

Gene Information

Entrez Gene ID24680
Gene Nameprotein kinase C, alpha
Gene SymbolPrkca
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 ISS:UniProtKBCcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0045121 IDA:RGDCmembrane raft
GO:0005739 IDA:RGDCmitochondrion
GO:0043005 IDA:RGDCneuron projection
GO:0005634 IEA:UniProtKB-KWCnucleus
GO:0048471 IDA:UniProtKBCperinuclear region of cytoplasm
GO:0005886 IDA:RGDCplasma membrane
GO:0043234 IDA:RGDCprotein complex
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004698 IDA:RGDFcalcium-dependent protein kinase C activity
GO:0004697 IDA:RGDFprotein kinase C activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0007568 IEP:RGDPaging
GO:0001525 IEA:UniProtKB-KWPangiogenesis
GO:0006915 IEA:UniProtKB-KWPapoptotic process
GO:0007155 IEA:UniProtKB-KWPcell adhesion
GO:0021955 IMP:RGDPcentral nervous system neuron axonogenesis
GO:0045184 TAS:UniProtKBPestablishment of protein localization
GO:0035556 IDA:RGDPintracellular signal transduction
GO:0007611 IMP:RGDPlearning or memory
GO:0034351 ISS:UniProtKBPnegative regulation of glial cell apoptotic process
GO:0045822 IMP:RGDPnegative regulation of heart contraction
GO:0017148 IMP:RGDPnegative regulation of translation
GO:0018105 IDA:RGDPpeptidyl-serine phosphorylation
GO:0018107 IDA:RGDPpeptidyl-threonine phosphorylation
GO:0045766 ISS:UniProtKBPpositive regulation of angiogenesis
GO:0010613 IDA:UniProtKBPpositive regulation of cardiac muscle hypertrophy
GO:0045785 ISS:UniProtKBPpositive regulation of cell adhesion
GO:0030335 ISS:UniProtKBPpositive regulation of cell migration
GO:2000707 ISS:UniProtKBPpositive regulation of dense core granule biogenesis
GO:0010595 ISS:UniProtKBPpositive regulation of endothelial cell migration
GO:0001938 ISS:UniProtKBPpositive regulation of endothelial cell proliferation
GO:0070374 IMP:UniProtKBPpositive regulation of ERK1 and ERK2 cascade
GO:0045921 IMP:RGDPpositive regulation of exocytosis
GO:0031666 ISS:UniProtKBPpositive regulation of lipopolysaccharide-mediated signaling pathway
GO:0045651 ISS:UniProtKBPpositive regulation of macrophage differentiation
GO:0045931 ISS:UniProtKBPpositive regulation of mitotic cell cycle
GO:0048661 IMP:RGDPpositive regulation of smooth muscle cell proliferation
GO:0051965 IMP:RGDPpositive regulation of synapse assembly
GO:0046777 IDA:RGDPprotein autophosphorylation
GO:0006468 IDA:RGDPprotein phosphorylation
GO:0090330 ISS:UniProtKBPregulation of platelet aggregation
GO:0048259 IMP:RGDPregulation of receptor-mediated endocytosis
GO:0046677 IEP:RGDPresponse to antibiotic
GO:0051412 IEP:RGDPresponse to corticosterone
GO:0032355 IMP:RGDPresponse to estradiol
GO:0045471 IMP:RGDPresponse to ethanol
GO:0009612 IEP:RGDPresponse to mechanical stimulus
GO:0014070 IEP:RGDPresponse to organic cyclic compound
GO:0043434 IEP:RGDPresponse to peptide hormone
GO:0000302 IMP:RGDPresponse to reactive oxygen species
GO:0009636 IEP:RGDPresponse to toxic substance
KEGG Pathway Links
KEGG Pathway IDDescription
ko04261Adrenergic signaling in cardiomyocytes
rno04261Adrenergic signaling in cardiomyocytes
ko05143African trypanosomiasis
rno05143African trypanosomiasis
ko04960Aldosterone-regulated sodium reabsorption
rno04960Aldosterone-regulated sodium reabsorption
ko05146Amoebiasis
rno05146Amoebiasis
ko05031Amphetamine addiction
rno05031Amphetamine addiction
ko04020Calcium signaling pathway
rno04020Calcium signaling pathway
rno04725Cholinergic synapse
ko04713Circadian entrainment
rno04713Circadian entrainment
ko04728Dopaminergic synapse
rno04728Dopaminergic synapse
ko04961Endocrine and other factor-regulated calcium reabsorption
rno04961Endocrine and other factor-regulated calcium reabsorption
ko04012ErbB signaling pathway
rno04012ErbB signaling pathway
ko04664Fc epsilon RI signaling pathway
rno04664Fc epsilon RI signaling pathway
ko04666Fc gamma R-mediated phagocytosis
rno04666Fc gamma R-mediated phagocytosis
ko04510Focal adhesion
rno04510Focal adhesion
ko04727GABAergic synapse
rno04727GABAergic synapse
ko04540Gap junction
rno04540Gap junction
ko04971Gastric acid secretion
rno04971Gastric acid secretion
ko05214Glioma
rno05214Glioma
ko04724Glutamatergic synapse
rno04724Glutamatergic synapse
ko04912GnRH signaling pathway
rno04912GnRH signaling pathway
rno05161Hepatitis B
rno04066HIF-1 signaling pathway
ko04750Inflammatory mediator regulation of TRP channels
rno04750Inflammatory mediator regulation of TRP channels
ko05164Influenza A
rno05164Influenza A
rno04911Insulin secretion
ko04670Leukocyte transendothelial migration
rno04670Leukocyte transendothelial migration
ko04730Long-term depression
rno04730Long-term depression
ko04720Long-term potentiation
rno04720Long-term potentiation
ko04010MAPK signaling pathway
rno04010MAPK signaling pathway
ko04916Melanogenesis
rno04916Melanogenesis
ko05206MicroRNAs in cancer
rno05206MicroRNAs in cancer
ko05032Morphine addiction
rno05032Morphine addiction
ko04150mTOR signaling pathway
rno04150mTOR signaling pathway
ko04650Natural killer cell mediated cytotoxicity
rno04650Natural killer cell mediated cytotoxicity
ko05223Non-small cell lung cancer
rno05223Non-small cell lung cancer
ko04921Oxytocin signaling pathway
rno04921Oxytocin signaling pathway
ko04972Pancreatic secretion
rno04972Pancreatic secretion
rno05200Pathways in cancer
ko04070Phosphatidylinositol signaling system
rno04070Phosphatidylinositol signaling system
ko04151PI3K-Akt signaling pathway
rno04151PI3K-Akt signaling pathway
ko05205Proteoglycans in cancer
rno05205Proteoglycans in cancer
ko04015Rap1 signaling pathway
rno04015Rap1 signaling pathway
rno04014Ras signaling pathway
ko04723Retrograde endocannabinoid signaling
rno04723Retrograde endocannabinoid signaling
ko04970Salivary secretion
rno04970Salivary secretion
rno04726Serotonergic synapse
rno04919Thyroid hormone signaling pathway
ko04918Thyroid hormone synthesis
rno04918Thyroid hormone synthesis
ko04530Tight junction
rno04530Tight junction
ko04270Vascular smooth muscle contraction
rno04270Vascular smooth muscle contraction
ko04370VEGF signaling pathway
rno04370VEGF signaling pathway
ko04310Wnt signaling pathway
rno04310Wnt signaling pathway