LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP012468

Gene Information

Entrez Gene ID25086
Gene Namecytochrome P450, family 2, subfamily e, polypeptide 1
Gene SymbolCyp2e1
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0000139 IDA:RGDCGolgi membrane
GO:0043231 IDA:RGDCintracellular membrane-bounded organelle
GO:0031227 IDA:RGDCintrinsic component of endoplasmic reticulum membrane
GO:0005739 IDA:RGDCmitochondrion
GO:0010181 IC:RGDFFMN binding
GO:0020037 ISS:UniProtKBFheme binding
GO:0005506 IEA:InterProFiron ion binding
GO:0004497 TAS:RGDFmonooxygenase activity
GO:0016709 IEA:UniProtKB-ECFoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0016712 IDA:RGDFoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0017144 IEA:EnsemblPdrug metabolic process
GO:0046483 IEA:EnsemblPheterocycle metabolic process
GO:0016098 IEA:EnsemblPmonoterpenoid metabolic process
GO:0055114 IDA:RGDPoxidation-reduction process
GO:0042493 IEP:RGDPresponse to drug
GO:0045471 IEP:RGDPresponse to ethanol
GO:0010243 IEP:RGDPresponse to organonitrogen compound
GO:0010193 IEP:RGDPresponse to ozone
GO:0008202 IEA:EnsemblPsteroid metabolic process
GO:0006641 IMP:RGDPtriglyceride metabolic process
GO:0006805 IMP:RGDPxenobiotic metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
ko00590Arachidonic acid metabolism
rno00590Arachidonic acid metabolism
ko05204Chemical carcinogenesis
rno05204Chemical carcinogenesis
ko00982Drug metabolism - cytochrome P450
rno00982Drug metabolism - cytochrome P450
ko00591Linoleic acid metabolism
rno00591Linoleic acid metabolism
rno01100Metabolic pathways
ko00980Metabolism of xenobiotics by cytochrome P450
rno00980Metabolism of xenobiotics by cytochrome P450
ko04932Non-alcoholic fatty liver disease (NAFLD)
rno04932Non-alcoholic fatty liver disease (NAFLD)
ko00140Steroid hormone biosynthesis
rno00140Steroid hormone biosynthesis
REACTOME Pathway Links
REACTOME Pathway IDDescription
5953258Biological oxidations
5953483CYP2E1 reactions
5953485Cytochrome P450 - arranged by substrate type
5953250Metabolism
5953326Phase 1 - Functionalization of compounds
5953484Xenobiotics