LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP012471

Gene Information

Entrez Gene ID25114
Gene Namefibroblast growth factor receptor 4
Gene SymbolFgfr4
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005911 IEA:EnsemblCcell-cell junction
GO:0005783 ISS:UniProtKBCendoplasmic reticulum
GO:0005768 IEA:UniProtKB-KWCendosome
GO:0005887 ISS:UniProtKBCintegral component of plasma membrane
GO:0005634 IEA:EnsemblCnucleus
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0005007 IPI:MGIFfibroblast growth factor-activated receptor activity
GO:0017134 ISS:UniProtKBFfibroblast growth factor binding
GO:0008201 ISS:UniProtKBFheparin binding
GO:0061144 IEA:EnsemblPalveolar secondary septum development
GO:0016477 ISS:UniProtKBPcell migration
GO:0008543 IPI:MGIPfibroblast growth factor receptor signaling pathway
GO:0042593 ISS:UniProtKBPglucose homeostasis
GO:0001759 IEA:EnsemblPorgan induction
GO:0018108 ISS:UniProtKBPpeptidyl-tyrosine phosphorylation
GO:0055062 ISS:UniProtKBPphosphate ion homeostasis
GO:0008284 ISS:UniProtKBPpositive regulation of cell proliferation
GO:2000573 ISS:UniProtKBPpositive regulation of DNA biosynthetic process
GO:0070374 ISS:UniProtKBPpositive regulation of ERK1 and ERK2 cascade
GO:0048554 ISS:UniProtKBPpositive regulation of metalloenzyme activity
GO:0045862 ISS:UniProtKBPpositive regulation of proteolysis
GO:0046777 ISS:UniProtKBPprotein autophosphorylation
GO:0070857 ISS:UniProtKBPregulation of bile acid biosynthetic process
GO:2000188 ISS:UniProtKBPregulation of cholesterol homeostasis
GO:0010715 ISS:UniProtKBPregulation of extracellular matrix disassembly
GO:0019216 ISS:UniProtKBPregulation of lipid metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
ko04144Endocytosis
rno04144Endocytosis
ko04010MAPK signaling pathway
rno04010MAPK signaling pathway
ko04151PI3K-Akt signaling pathway
rno04151PI3K-Akt signaling pathway
ko04015Rap1 signaling pathway
rno04015Rap1 signaling pathway
rno04014Ras signaling pathway
ko04810Regulation of actin cytoskeleton
rno04810Regulation of actin cytoskeleton
ko04550Signaling pathways regulating pluripotency of stem cells
rno04550Signaling pathways regulating pluripotency of stem cells
REACTOME Pathway Links
REACTOME Pathway IDDescription
5953415Adaptive Immune System
5954452betaKlotho-mediated ligand binding
5954570Constitutive PI3K/AKT Signaling in Cancer
5953408DAP12 interactions
5953407DAP12 signaling
5953253Disease
5953994Downstream signaling events of B Cell Receptor (BCR)
5953399Downstream signaling of activated FGFR
5953396Downstream signal transduction
5953417Fc epsilon receptor (FCERI) signaling
5953909FGFR4 ligand binding and activation
5953902FGFR ligand binding and activation
5953530FRS2-mediated cascade
5953884GAB1 signalosome
5953430IGF1R signaling cascade
5953410Immune System
5953409Innate Immune System
5953422Insulin receptor signalling cascade
5953428IRS-mediated signalling
5953425IRS-related events
5953429IRS-related events triggered by IGF1R
5953911Klotho-mediated ligand binding
5954379Negative regulation of FGFR signaling
5953394NGF signalling via TRKA from the plasma membrane
5953398Phospholipase C-mediated cascade
5953989PI3K/AKT activation
5953997PI3K/AKT Signaling in Cancer
5953885PI-3K cascade
5953432PI3K Cascade
5953996PI3K events in ERBB2 signaling
5953995PI3K events in ERBB4 signaling
5953993PIP3 activates AKT signaling
5953998Role of LAT2/NTAL/LAB on calcium mobilization
5954432SHC-mediated cascade
5953403Signaling by EGFR
5953404Signaling by EGFR in Cancer
5953406Signaling by ERBB2
5953540Signaling by ERBB4
5953400Signaling by FGFR
5954532Signaling by FGFR4 mutants
5953401Signaling by FGFR in disease
5954512Signaling by FGFR mutants
5953423Signaling by Insulin receptor
5953397Signaling by PDGF
5953541Signaling by SCF-KIT
5953414Signaling by the B Cell Receptor (BCR)
5953431Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
5953395Signalling by NGF
5953381Signal Transduction