LIPID MAPS® Gene/Proteome Database (LMPD)

LMPD Record

LMP012612

Entrez Gene ID	29577
Gene Name	hes family bHLH transcription factor 1
Gene Symbol	Hes1
Species	Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005654	TAS:Reactome	C	nucleoplasm
GO:0005634	ISS:UniProtKB	C	nucleus
GO:0071820	ISS:UniProtKB	F	N-box binding
GO:0042803	ISS:UniProtKB	F	protein homodimerization activity
GO:0001078	ISS:UniProtKB	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0043565	IDA:BHF-UCL	F	sequence-specific DNA binding
GO:0021861	IDA:UniProtKB	P	forebrain radial glial cell differentiation
GO:2000978	IDA:UniProtKB	P	negative regulation of forebrain neuron differentiation
GO:0060253	ISS:UniProtKB	P	negative regulation of glial cell proliferation
GO:0048715	ISS:UniProtKB	P	negative regulation of oligodendrocyte differentiation
GO:2000974	ISS:UniProtKB	P	negative regulation of pro-B cell differentiation
GO:0045892	IDA:UniProtKB	P	negative regulation of transcription, DNA-templated
GO:0000122	IDA:UniProtKB	P	negative regulation of transcription from RNA polymerase II promoter
GO:0097150	IDA:UniProtKB	P	neuronal stem cell maintenance
GO:0048711	ISS:UniProtKB	P	positive regulation of astrocyte differentiation
GO:0043388	ISS:UniProtKB	P	positive regulation of DNA binding
GO:0046427	ISS:UniProtKB	P	positive regulation of JAK-STAT cascade
GO:0042517	ISS:UniProtKB	P	positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0006461	ISS:UniProtKB	P	protein complex assembly
GO:0007262	ISS:UniProtKB	P	STAT protein import into nucleus

KEGG Pathway Links

KEGG Pathway ID	Description
ko03460	Fanconi anemia pathway
rno03460	Fanconi anemia pathway
ko04950	Maturity onset diabetes of the young
rno04950	Maturity onset diabetes of the young
ko04330	Notch signaling pathway
rno04330	Notch signaling pathway