LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP012623

Record overview

LMPD IDLMP012623
Gene ID29680
SpeciesMacaca mulata (Rhesus monkey)
Gene Namecytochrome P450, family 11, subfamily a, polypeptide 1
Gene SymbolCyp11a1
SynonymsCyp11a; Cypxia1; P450scc;
Alternate namescholesterol side-chain cleavage enzyme, mitochondrial; P450(scc); cytochrome P450 11A1; cytochrome P450(scc); cholesterol desmolase; cytochrome P450 subfamily 11A; cytochrome P450 side-chain cleavage enzyme; cholesterol side-chain cleavage cytochrome P450; cytochrome P450 11a cholesterol side chain cleavage;
Chromosome8
Map Location8q24
EC Number1.14.15.6
Summarymonooxygenase that catalyzes synthesis of cholesterol and steroids [RGD, Feb 2006]
OrthologsView orthologs and multiple alignments for Cyp11a1

Proteins

cholesterol side-chain cleavage enzyme, mitochondrial precursor
Refseq ID:NP_058982
Protein GI:8393224
UniProt ID:P14137
mRNA ID:NM_017286
Length:526
RefSeq Status:
MLAKGLCLRSVLVKSCQPFLSPVWQGPGLATGNGAGISSTNSPRSFNEIPSPGDNGWINLYHFLRENGTHRIHYHHMQNFQKYGPIYREKLGNMESVYIL
DPKDAATLFSCEGPNPERYLVPPWVAYHQYYQRPIGVLFKSSDAWRKDRIVLNQEVMAPDSIKNFVPLLEGVAQDFIKVLHRRIKQQNSGKFSGDISDDL
FRFAFESITSVVFGERLGMLEEIVDPESQRFIDAVYQMFHTSVPMLNMPPDLFRLFRTKTWKDHAAAWDVIFSKADEYTQNFYWDLRQKRDFSKYPGVLY
SLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEVLAARRQAQGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYIVNDLV
LRNYKIPAKTLVQVASYAMGRESSFFPNPNKFDPTRWLEKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENFRIEVQSIRDVGTKFNLILMP
EKPIFFNFQPLKQDLGSTMPRKGDTV
 

transit_peptide: 1..36
experiment: experimental evidence, no additional details recorded
note: Mitochondrion; propagated from UniProtKB/Swiss-Prot (P14137.1)
calculated_mol_wt: 3657
peptide sequence: 
MLAKGLCLRSVLVKSCQPFLSPVWQGPGLATGNGAG

mat_peptide: 37..526
product: Cholesterol side-chain cleavage enzyme, mitochondrial
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P14137.1)
calculated_mol_wt: 56947
peptide sequence: 
ISSTNSPRSFNEIPSPGDNGWINLYHFLRENGTHRIHYHHMQNFQKYGPIYREKLGNMESVYILDPKDAATLFSCEGPNPERYLVPPWVAYHQYYQRPIG
VLFKSSDAWRKDRIVLNQEVMAPDSIKNFVPLLEGVAQDFIKVLHRRIKQQNSGKFSGDISDDLFRFAFESITSVVFGERLGMLEEIVDPESQRFIDAVY
QMFHTSVPMLNMPPDLFRLFRTKTWKDHAAAWDVIFSKADEYTQNFYWDLRQKRDFSKYPGVLYSLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWNL
YEMAHNLKVQEMLRAEVLAARRQAQGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYIVNDLVLRNYKIPAKTLVQVASYAMGRESSFFPNPNKFDPTR
WLEKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENFRIEVQSIRDVGTKFNLILMPEKPIFFNFQPLKQDLGSTMPRKGDTV