LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP012651

UniProt Annotations

Entry Information
Gene Namepalmitoyl-protein thioesterase 2
Protein EntryPPT2_RAT
UniProt IDO70489
SpeciesRat
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=O70489-1; Sequence=Displayed; Name=2; Synonyms=Truncated; IsoId=O70489-2; Sequence=VSP_005189, VSP_005190;
Catalytic ActivityPalmitoyl-protein + H(2)O = palmitate + protein.
FunctionRemoves thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S- thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins (By similarity)
SimilarityBelongs to the palmitoyl-protein thioesterase family
Subcellular LocationLysosome .