LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP012711

Gene Information

Entrez Gene ID64562
Gene Nameprotein kinase, AMP-activated, beta 2 non-catalytic subunit
Gene SymbolPrkab2
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031588 IDA:RGDCAMP-activated protein kinase complex
GO:0016324 IDA:UniProtKBCapical plasma membrane
GO:0005952 IDA:RGDCcAMP-dependent protein kinase complex
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0019901 IPI:RGDFprotein kinase binding
GO:0006633 IEA:UniProtKB-KWPfatty acid biosynthetic process
GO:0006468 ISS:GOCPprotein phosphorylation
KEGG Pathway Links
KEGG Pathway IDDescription
ko04920Adipocytokine signaling pathway
rno04920Adipocytokine signaling pathway
ko04152AMPK signaling pathway
rno04152AMPK signaling pathway
ko04710Circadian rhythm
rno04710Circadian rhythm
rno04068FoxO signaling pathway
ko05410Hypertrophic cardiomyopathy (HCM)
rno05410Hypertrophic cardiomyopathy (HCM)
ko04910Insulin signaling pathway
rno04910Insulin signaling pathway
ko04932Non-alcoholic fatty liver disease (NAFLD)
rno04932Non-alcoholic fatty liver disease (NAFLD)
ko04921Oxytocin signaling pathway
rno04921Oxytocin signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
5954481Activation of PPARGC1A (PGC-1alpha) by phosphorylation
5953759AMPK inhibits chREBP transcriptional activation activity
5954019Energy dependent regulation of mTOR by LKB1-AMPK
5953288Fatty acid, triacylglycerol, and ketone body metabolism
5953430IGF1R signaling cascade
5953467Import of palmitoyl-CoA into the mitochondrial matrix
5953422Insulin receptor signalling cascade
5953611Integration of energy metabolism
5953428IRS-mediated signalling
5953425IRS-related events
5953429IRS-related events triggered by IGF1R
5953916Membrane Trafficking
5953250Metabolism
5953289Metabolism of lipids and lipoproteins
5953600Mitochondrial biogenesis
5953766mTOR signalling
5953601Organelle biogenesis and maintenance
5953432PI3K Cascade
5953733PKB-mediated events
5954018Regulation of AMPK activity via LKB1
5954161Regulation of Rheb GTPase activity by AMPK
5953423Signaling by Insulin receptor
5953431Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
5953381Signal Transduction
5954455Translocation of GLUT4 to the plasma membrane