LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP013257

UniProt Annotations

Entry Information
Gene Namesolute carrier family 10, member 4
Protein EntryNTCP4_RAT
UniProt IDQ5PT56
SpeciesRat
Comments
Comment typeDescription
FunctionTransporter for bile acids
PtmActivated following N-terminal proteolytic cleavage by thrombin and/or proteases
SimilarityBelongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family
Subcellular LocationCell membrane ; Multi-pass membrane protein .
Tissue SpecificityMainly expressed in the central nervous system cholinergic neurons. Expressed (at protein level) in motor regions of the spinal cord and rhombencephalon, in mesopontine cholinergic neurons, the medial habenula, cholinergic areas of the forebrain, and the gut myenteric plexus