LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP013462

UniProt Annotations

Entry Information
Gene NameELOVL fatty acid elongase 7
Protein EntryELOV7_RAT
UniProt IDD4ADY9
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityA very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2).
DomainThe di-lysine motif may confer endoplasmic reticulum localization
FunctionCondensing enzyme that catalyzes the synthesis of saturated and polyunsaturated very long chain fatty acids. Highest activity toward C18 acyl-CoAs (By similarity)
SimilarityBelongs to the ELO family
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein .