LIPID MAPS® Gene/Proteome Database (LMPD)

Introduction | Overview of Interfaces | Browse | Search | Download

LMPD Record

LMP014605

Gene Information

Entrez Gene ID	718387
Gene Name	phospholipase C, beta 1 (phosphoinositide-specific)
Gene Symbol	PLCB1
Species	Macaca mulatta

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IEA:Ensembl	C	cytoplasm
GO:0070062	IEA:Ensembl	C	extracellular vesicular exosome
GO:0000790	IEA:Ensembl	C	nuclear chromatin
GO:0016607	IEA:Ensembl	C	nuclear speck
GO:0005509	IEA:InterPro	F	calcium ion binding
GO:0005096	IEA:Ensembl	F	GTPase activator activity
GO:0005546	IEA:Ensembl	F	phosphatidylinositol-4,5-bisphosphate binding
GO:0004435	IEA:UniProtKB-EC	F	phosphatidylinositol phospholipase C activity
GO:0004871	IEA:UniProtKB-KW	F	signal transducer activity
GO:0060466	IEA:Ensembl	P	activation of meiosis involved in egg activation
GO:0021987	IEA:Ensembl	P	cerebral cortex development
GO:0045444	IEA:Ensembl	P	fat cell differentiation
GO:0007215	IEA:Ensembl	P	glutamate receptor signaling pathway
GO:0007213	IEA:Ensembl	P	G-protein coupled acetylcholine receptor signaling pathway
GO:0048009	IEA:Ensembl	P	insulin-like growth factor receptor signaling pathway
GO:0035722	IEA:Ensembl	P	interleukin-12-mediated signaling pathway
GO:0035723	IEA:Ensembl	P	interleukin-15-mediated signaling pathway
GO:0070498	IEA:Ensembl	P	interleukin-1-mediated signaling pathway
GO:0035556	IEA:InterPro	P	intracellular signal transduction
GO:0016042	IEA:UniProtKB-KW	P	lipid catabolic process
GO:0007613	IEA:Ensembl	P	memory
GO:2000438	IEA:Ensembl	P	negative regulation of monocyte extravasation
GO:0045892	IEA:Ensembl	P	negative regulation of transcription, DNA-templated
GO:2000344	IEA:Ensembl	P	positive regulation of acrosome reaction
GO:2000560	IEA:Ensembl	P	positive regulation of CD24 biosynthetic process
GO:0048639	IEA:Ensembl	P	positive regulation of developmental growth
GO:0040019	IEA:Ensembl	P	positive regulation of embryonic development
GO:1900087	IEA:Ensembl	P	positive regulation of G1/S transition of mitotic cell cycle
GO:0032735	IEA:Ensembl	P	positive regulation of interleukin-12 production
GO:0046330	IEA:Ensembl	P	positive regulation of JNK cascade
GO:0045663	IEA:Ensembl	P	positive regulation of myoblast differentiation
GO:0045893	IEA:Ensembl	P	positive regulation of transcription, DNA-templated
GO:0080154	IEA:Ensembl	P	regulation of fertilization
GO:0008277	IEA:Ensembl	P	regulation of G-protein coupled receptor protein signaling pathway

KEGG Pathway Links

KEGG Pathway ID	Description
ko04261	Adrenergic signaling in cardiomyocytes
mcc04261	Adrenergic signaling in cardiomyocytes
ko05143	African trypanosomiasis
mcc05143	African trypanosomiasis
ko05010	Alzheimer's disease
mcc05010	Alzheimer's disease
ko05146	Amoebiasis
mcc05146	Amoebiasis
ko04020	Calcium signaling pathway
mcc04020	Calcium signaling pathway
ko04022	cGMP-PKG signaling pathway
mcc04022	cGMP-PKG signaling pathway
ko05142	Chagas disease (American trypanosomiasis)
mcc05142	Chagas disease (American trypanosomiasis)
ko04062	Chemokine signaling pathway
mcc04062	Chemokine signaling pathway
mcc04725	Cholinergic synapse
ko04713	Circadian entrainment
mcc04713	Circadian entrainment
ko04728	Dopaminergic synapse
mcc04728	Dopaminergic synapse
ko04961	Endocrine and other factor-regulated calcium reabsorption
mcc04961	Endocrine and other factor-regulated calcium reabsorption
ko04915	Estrogen signaling pathway
mcc04915	Estrogen signaling pathway
ko04540	Gap junction
mcc04540	Gap junction
ko04971	Gastric acid secretion
mcc04971	Gastric acid secretion
ko04724	Glutamatergic synapse
mcc04724	Glutamatergic synapse
ko04912	GnRH signaling pathway
mcc04912	GnRH signaling pathway
ko05016	Huntington's disease
mcc05016	Huntington's disease
ko04750	Inflammatory mediator regulation of TRP channels
mcc04750	Inflammatory mediator regulation of TRP channels
ko00562	Inositol phosphate metabolism
mcc00562	Inositol phosphate metabolism
M00130	Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
mcc_M00130	Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
mcc04911	Insulin secretion
ko04730	Long-term depression
mcc04730	Long-term depression
ko04720	Long-term potentiation
mcc04720	Long-term potentiation
ko04916	Melanogenesis
mcc04916	Melanogenesis
mcc01100	Metabolic pathways
ko04921	Oxytocin signaling pathway
mcc04921	Oxytocin signaling pathway
ko04972	Pancreatic secretion
mcc04972	Pancreatic secretion
ko04070	Phosphatidylinositol signaling system
mcc04070	Phosphatidylinositol signaling system
mcc04611	Platelet activation
ko04015	Rap1 signaling pathway
mcc04015	Rap1 signaling pathway
ko04723	Retrograde endocannabinoid signaling
mcc04723	Retrograde endocannabinoid signaling
ko04970	Salivary secretion
mcc04970	Salivary secretion
mcc04726	Serotonergic synapse
mcc04919	Thyroid hormone signaling pathway
ko04918	Thyroid hormone synthesis
mcc04918	Thyroid hormone synthesis
ko04270	Vascular smooth muscle contraction
mcc04270	Vascular smooth muscle contraction
ko04310	Wnt signaling pathway
mcc04310	Wnt signaling pathway