LMPD Database

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LMP000013

Gene Information

Entrez Gene ID18720
Gene Namephosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
Gene SymbolPip5k1a
SpeciesMus musculus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IEA:UniProtKB-KWCcytoplasm
GO:0030027 IEA:EnsemblClamellipodium
GO:0005847 IEA:EnsemblCmRNA cleavage and polyadenylation specificity factor complex
GO:0016607 ISS:UniProtKBCnuclear speck
GO:0005634 IDA:MGICnucleus
GO:0005886 ISS:UniProtKBCplasma membrane
GO:0032587 IDA:MGICruffle membrane
GO:0016308 IDA:MGIF1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0031532 ISS:UniProtKBPactin cytoskeleton reorganization
GO:0032863 ISS:UniProtKBPactivation of Rac GTPase activity
GO:0060326 ISS:UniProtKBPcell chemotaxis
GO:0010761 IMP:MGIPfibroblast migration
GO:0048041 ISS:UniProtKBPfocal adhesion assembly
GO:0046488 IDA:MGIPphosphatidylinositol metabolic process
GO:0046854 IDA:GOCPphosphatidylinositol phosphorylation
GO:0008654 IEA:EnsemblPphospholipid biosynthetic process
GO:0072661 ISS:UniProtKBPprotein targeting to plasma membrane
GO:0097178 ISS:UniProtKBPruffle assembly
KEGG Pathway Links
KEGG Pathway IDDescription
ko04144Endocytosis
mmu04144Endocytosis
ko04666Fc gamma R-mediated phagocytosis
mmu04666Fc gamma R-mediated phagocytosis
ko00562Inositol phosphate metabolism
mmu00562Inositol phosphate metabolism
M00130Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
mmu01100Metabolic pathways
ko04070Phosphatidylinositol signaling system
mmu04070Phosphatidylinositol signaling system
ko04810Regulation of actin cytoskeleton
mmu04810Regulation of actin cytoskeleton
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY-63523-phosphoinositide biosynthesis
PWY-6351D-myo-inositol (1,4,5)-trisphosphate biosynthesis
PWY3DJ-219PIP metabolism
REACTOME Pathway Links
REACTOME Pathway IDDescription
5892760Metabolism
5892799Metabolism of lipids and lipoproteins
5892984Phospholipid metabolism
5893988PI Metabolism
5894009Synthesis of PIPs at the plasma membrane