LMPD Database

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LMP000047

Gene Information

Entrez Gene ID3949
Gene Namelow density lipoprotein receptor
Gene SymbolLDLR
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:UniProtKBCcell surface
GO:0030669 TAS:ReactomeCclathrin-coated endocytic vesicle membrane
GO:0005905 IDA:BHF-UCLCcoated pit
GO:0005769 IDA:UniProtKBCearly endosome
GO:0010008 TAS:ReactomeCendosome membrane
GO:0009897 IDA:BHF-UCLCexternal side of plasma membrane
GO:0005794 IDA:UniProtKBCGolgi apparatus
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005770 IDA:UniProtKBClate endosome
GO:0034362 IEA:UniProtKB-KWClow-density lipoprotein particle
GO:0005764 IDA:UniProtKBClysosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0043235 IDA:MGICreceptor complex
GO:0005509 IEA:InterProFcalcium ion binding
GO:0001948 IPI:BHF-UCLFglycoprotein binding
GO:0030169 IEA:EnsemblFlow-density lipoprotein particle binding
GO:0005041 IDA:BHF-UCLFlow-density lipoprotein receptor activity
GO:0030229 IDA:BHF-UCLFvery-low-density lipoprotein particle receptor activity
GO:0042632 IMP:BHF-UCLPcholesterol homeostasis
GO:0070508 ISS:BHF-UCLPcholesterol import
GO:0008203 IEA:UniProtKB-KWPcholesterol metabolic process
GO:0030301 IMP:HGNCPcholesterol transport
GO:0006897 TAS:ProtIncPendocytosis
GO:0030299 IMP:HGNCPintestinal cholesterol absorption
GO:0006629 TAS:ProtIncPlipid metabolic process
GO:0042159 IEA:EnsemblPlipoprotein catabolic process
GO:0042157 TAS:ReactomePlipoprotein metabolic process
GO:0034383 IMP:BHF-UCLPlow-density lipoprotein particle clearance
GO:0015914 ISS:BHF-UCLPphospholipid transport
GO:0007603 TAS:ReactomePphototransduction, visible light
GO:0010867 ISS:BHF-UCLPpositive regulation of triglyceride biosynthetic process
GO:0006898 TAS:ReactomePreceptor-mediated endocytosis
GO:2000188 IEA:EnsemblPregulation of cholesterol homeostasis
GO:0010899 ISS:BHF-UCLPregulation of phosphatidylcholine catabolic process
GO:0001523 TAS:ReactomePretinoid metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0016032 IEA:UniProtKB-KWPviral process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04913Ovarian steroidogenesis