LMPD Database

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LMP000051

UniProt Annotations

Entry Information
Gene Namelysophosphatidic acid receptor 3
Protein EntryLPAR3_HUMAN
UniProt IDQ9UBY5
SpeciesHuman
Comments
Comment typeDescription
FunctionReceptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.
SimilarityBelongs to the G-protein coupled receptor 1 family.
Subcellular LocationCell membrane; Multi-pass membrane protein.
Tissue SpecificityMost abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes.