LMPD Database

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LMP000057

UniProt Annotations

Entry Information
Gene Namehydroxysteroid (17-beta) dehydrogenase 1
Protein EntryDHB1_MOUSE
UniProt IDP51656
SpeciesMouse
Comments
Comment typeDescription
Catalytic Activity17-beta-estradiol + NAD(P)(+) = estrone + NAD(P)H.
FunctionFavors the reduction of estrogens and androgens. Uses preferentially NADH.
PathwaySteroid biosynthesis; estrogen biosynthesis.
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family. {ECO:0000305}.
Subcellular LocationCytoplasm.
SubunitHomodimer. {ECO:0000250}.