LMPD Database

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LMP000169

UniProt Annotations

Entry Information
Gene Namehexosaminidase B
Protein EntryHEXB_MOUSE
UniProt IDP20060
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityHydrolysis of terminal non-reducing N-acetyl- D-hexosamine residues in N-acetyl-beta-D-hexosaminides.
FunctionResponsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.
SimilarityBelongs to the glycosyl hydrolase 20 family. {ECO:0000305}.
Subcellular LocationLysosome.