LMPD Database

LMP000216

Gene Information

Entrez Gene ID	5914
Gene Name	retinoic acid receptor, alpha
Gene Symbol	RARA
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009986	IC:BHF-UCL	C	cell surface
GO:0005737	IDA:UniProtKB	C	cytoplasm
GO:0030425	IEA:Ensembl	C	dendrite
GO:0043025	IEA:Ensembl	C	neuronal cell body
GO:0000790	IDA:BHF-UCL	C	nuclear chromatin
GO:0005654	TAS:Reactome	C	nucleoplasm
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0048471	IEA:Ensembl	C	perinuclear region of cytoplasm
GO:0031490	IDA:UniProtKB	F	chromatin DNA binding
GO:0008144	IEA:Ensembl	F	drug binding
GO:0019899	IPI:UniProtKB	F	enzyme binding
GO:0048027	IEA:Ensembl	F	mRNA 5'-UTR binding
GO:0035014	IEA:Ensembl	F	phosphatidylinositol 3-kinase regulator activity
GO:0019904	IPI:UniProtKB	F	protein domain specific binding
GO:0046982	IDA:UniProtKB	F	protein heterodimerization activity
GO:0051018	IDA:UniProtKB	F	protein kinase A binding
GO:0043422	IPI:UniProtKB	F	protein kinase B binding
GO:0005102	IDA:UniProtKB	F	receptor binding
GO:0001972	IDA:BHF-UCL	F	retinoic acid binding
GO:0003708	IDA:BHF-UCL	F	retinoic acid receptor activity
GO:0044323	IDA:UniProtKB	F	retinoic acid-responsive element binding
GO:0000977	IEA:Ensembl	F	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003700	IDA:UniProtKB	F	sequence-specific DNA binding transcription factor activity
GO:0003707	IEA:InterPro	F	steroid hormone receptor activity
GO:0003713	IDA:UniProtKB	F	transcription coactivator activity
GO:0003714	IDA:UniProtKB	F	transcription corepressor activity
GO:0008134	IPI:UniProtKB	F	transcription factor binding
GO:0000900	IEA:Ensembl	F	translation repressor activity, nucleic acid binding
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0043277	IMP:UniProtKB	P	apoptotic cell clearance
GO:0071391	IDA:UniProtKB	P	cellular response to estrogen stimulus
GO:0071222	IEA:Ensembl	P	cellular response to lipopolysaccharide
GO:0071300	IDA:UniProtKB	P	cellular response to retinoic acid
GO:0060591	IEA:Ensembl	P	chondroblast differentiation
GO:0031076	IEA:Ensembl	P	embryonic camera-type eye development
GO:0060324	IEA:Ensembl	P	face development
GO:0007565	IEA:Ensembl	P	female pregnancy
GO:0010467	TAS:Reactome	P	gene expression
GO:0007281	IEA:Ensembl	P	germ cell development
GO:0002068	IEA:Ensembl	P	glandular epithelial cell development
GO:0003417	IEA:Ensembl	P	growth plate cartilage development
GO:0030520	IDA:BHF-UCL	P	intracellular estrogen receptor signaling pathway
GO:0060173	IEA:Ensembl	P	limb development
GO:0001889	IEA:Ensembl	P	liver development
GO:0035264	IEA:Ensembl	P	multicellular organism growth
GO:0043066	IEA:Ensembl	P	negative regulation of apoptotic process
GO:0061037	IEA:Ensembl	P	negative regulation of cartilage development
GO:0008285	IEA:Ensembl	P	negative regulation of cell proliferation
GO:0030853	IDA:UniProtKB	P	negative regulation of granulocyte differentiation
GO:0032689	IDA:BHF-UCL	P	negative regulation of interferon-gamma production
GO:0045892	IDA:UniProtKB	P	negative regulation of transcription, DNA-templated
GO:0000122	IEA:Ensembl	P	negative regulation of transcription from RNA polymerase II promoter
GO:0045947	IEA:Ensembl	P	negative regulation of translational initiation
GO:0032720	IDA:BHF-UCL	P	negative regulation of tumor necrosis factor production
GO:0001843	IEA:Ensembl	P	neural tube closure
GO:0003148	IEA:Ensembl	P	outflow tract septum morphogenesis
GO:0051099	IMP:UniProtKB	P	positive regulation of binding
GO:0045787	IMP:UniProtKB	P	positive regulation of cell cycle
GO:0008284	IMP:UniProtKB	P	positive regulation of cell proliferation
GO:0070374	IEA:Ensembl	P	positive regulation of ERK1 and ERK2 cascade
GO:0032736	IDA:BHF-UCL	P	positive regulation of interleukin-13 production
GO:0032753	IDA:BHF-UCL	P	positive regulation of interleukin-4 production
GO:0032754	IDA:BHF-UCL	P	positive regulation of interleukin-5 production
GO:0045666	IEA:Ensembl	P	positive regulation of neuron differentiation
GO:0014068	IEA:Ensembl	P	positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897	IEA:Ensembl	P	positive regulation of protein kinase B signaling
GO:0045630	IDA:BHF-UCL	P	positive regulation of T-helper 2 cell differentiation
GO:0045893	IDA:UniProtKB	P	positive regulation of transcription, DNA-templated
GO:0045944	IDA:UniProtKB	P	positive regulation of transcription from RNA polymerase II promoter
GO:0030850	IEA:Ensembl	P	prostate gland development
GO:0006468	IMP:UniProtKB	P	protein phosphorylation
GO:0031641	IEA:Ensembl	P	regulation of myelination
GO:0048167	IEA:Ensembl	P	regulation of synaptic plasticity
GO:0034097	IEA:Ensembl	P	response to cytokine
GO:0032355	IDA:BHF-UCL	P	response to estradiol
GO:0045471	IEA:Ensembl	P	response to ethanol
GO:0032526	IMP:BHF-UCL	P	response to retinoic acid
GO:0033189	IEA:Ensembl	P	response to vitamin A
GO:0048384	IMP:BHF-UCL	P	retinoic acid receptor signaling pathway
GO:0060010	IEA:Ensembl	P	Sertoli cell fate commitment
GO:0007165	IDA:BHF-UCL	P	signal transduction
GO:0007283	IEA:Ensembl	P	spermatogenesis
GO:0060534	IEA:Ensembl	P	trachea cartilage development
GO:0006367	TAS:Reactome	P	transcription initiation from RNA polymerase II promoter
GO:0001657	IEA:Ensembl	P	ureteric bud development
GO:0055012	IEA:Ensembl	P	ventricular cardiac muscle cell differentiation