LMPD Database

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LMP000375

UniProt Annotations

Entry Information
Gene Nameenoyl Coenzyme A hydratase, short chain, 1, mitochondrial
Protein EntryECHM_MOUSE
UniProt IDQ8BH95
SpeciesMouse
Comments
Comment typeDescription
Catalytic Activity(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl- CoA + H(2)O.
FunctionStraight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. {ECO:0000250}.
PathwayLipid metabolism; fatty acid beta-oxidation.
PtmAcetylation of Lys-101 is observed in liver mitochondria from fasted mice but not from fed mice. {ECO:0000269|PubMed:23576753}.
SimilarityBelongs to the enoyl-CoA hydratase/isomerase family. {ECO:0000305}.
Subcellular LocationMitochondrion matrix {ECO:0000250}.
SubunitHomohexamer; dimer of trimers. {ECO:0000250}.