LMPD Database

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LMP000519

UniProt Annotations

Entry Information
Gene Namealcohol dehydrogenase 5 (class III), chi polypeptide
Protein EntryADHX_HUMAN
UniProt IDP11766
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityAn alcohol + NAD(+) = an aldehyde or ketone + NADH.
Catalytic ActivityS-(hydroxymethyl)glutathione + NAD(P)(+) = S- formylglutathione + NAD(P)H.
CofactorName=Zn(2+); Xref=ChEBI
FunctionClass-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione.
MiscellaneousThere are 7 different ADH's isozymes in human: three belongs to class-I
SimilarityBelongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
Subcellular LocationCytoplasm.
SubunitHomodimer.
Web ResourceName=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/adh5/";