LMPD Database

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LMP000759

UniProt Annotations

Entry Information
Gene Nameprostaglandin D receptor
Protein EntryPD2R_MOUSE
UniProt IDP70263
SpeciesMouse
Comments
Comment typeDescription
FunctionReceptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity). {ECO:0000250}.
SimilarityBelongs to the G-protein coupled receptor 1 family. {ECO:0000255|PROSITE-ProRule:PRU00521}.
Subcellular LocationCell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue SpecificityMost abundantly expressed in the ileum, followed by lung, stomach and uterus.