LMPD Database

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LMP000880

UniProt Annotations

Entry Information
Gene Namesex hormone binding globulin
Protein EntrySHBG_MOUSE
UniProt IDP97497
SpeciesMouse
Comments
Comment typeDescription
FunctionFunctions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration (By similarity). {ECO:0000250}.
SimilarityContains 2 laminin G-like domains. {ECO:0000255|PROSITE-ProRule:PRU00122}.
Subcellular LocationSecreted {ECO:0000250}. Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis. {ECO:0000250}.
SubunitHomodimer. {ECO:0000250}.