LMPD Database

LMP000974

Gene Information

Entrez Gene ID	338
Gene Name	apolipoprotein B
Gene Symbol	APOB
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0015629	IDA:HPA	C	actin cytoskeleton
GO:0042627	IDA:BHF-UCL	C	chylomicron
GO:0034360	TAS:BHF-UCL	C	chylomicron remnant
GO:0030669	TAS:Reactome	C	clathrin-coated endocytic vesicle membrane
GO:0005737	IDA:UniProtKB	C	cytoplasm
GO:0005829	TAS:Reactome	C	cytosol
GO:0005769	TAS:Reactome	C	early endosome
GO:0071682	TAS:Reactome	C	endocytic vesicle lumen
GO:0005788	TAS:Reactome	C	endoplasmic reticulum lumen
GO:0005789	TAS:Reactome	C	endoplasmic reticulum membrane
GO:0031904	TAS:Reactome	C	endosome lumen
GO:0010008	TAS:Reactome	C	endosome membrane
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005615	ISS:BHF-UCL	C	extracellular space
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005794	IDA:HPA	C	Golgi apparatus
GO:0034363	IDA:BHF-UCL	C	intermediate-density lipoprotein particle
GO:0043231	TAS:ProtInc	C	intracellular membrane-bounded organelle
GO:0034362	IDA:BHF-UCL	C	low-density lipoprotein particle
GO:0034359	IDA:BHF-UCL	C	mature chylomicron
GO:0005886	IDA:HPA	C	plasma membrane
GO:0034361	IDA:BHF-UCL	C	very-low-density lipoprotein particle
GO:0017127	IMP:BHF-UCL	F	cholesterol transporter activity
GO:0008201	IDA:BHF-UCL	F	heparin binding
GO:0035473	IPI:BHF-UCL	F	lipase binding
GO:0050750	IMP:BHF-UCL	F	low-density lipoprotein particle receptor binding
GO:0005543	IDA:BHF-UCL	F	phospholipid binding
GO:0048844	IEA:Ensembl	P	artery morphogenesis
GO:0007596	TAS:Reactome	P	blood coagulation
GO:0071379	IEA:Ensembl	P	cellular response to prostaglandin stimulus
GO:0071356	IEA:Ensembl	P	cellular response to tumor necrosis factor
GO:0033344	IEA:Ensembl	P	cholesterol efflux
GO:0042632	IMP:BHF-UCL	P	cholesterol homeostasis
GO:0008203	IMP:BHF-UCL	P	cholesterol metabolic process
GO:0030301	IMP:BHF-UCL	P	cholesterol transport
GO:0009566	IEA:Ensembl	P	fertilization
GO:0001701	IEA:Ensembl	P	in utero embryonic development
GO:0050900	TAS:Reactome	P	leukocyte migration
GO:0042158	IEA:Ensembl	P	lipoprotein biosynthetic process
GO:0042159	IEA:Ensembl	P	lipoprotein catabolic process
GO:0042157	TAS:Reactome	P	lipoprotein metabolic process
GO:0042953	IEA:Ensembl	P	lipoprotein transport
GO:0034383	IMP:BHF-UCL	P	low-density lipoprotein particle clearance
GO:0034374	IMP:BHF-UCL	P	low-density lipoprotein particle remodeling
GO:0007399	IEA:Ensembl	P	nervous system development
GO:0007603	TAS:Reactome	P	phototransduction, visible light
GO:0010886	IDA:BHF-UCL	P	positive regulation of cholesterol storage
GO:0010884	IDA:BHF-UCL	P	positive regulation of lipid storage
GO:0010744	IDA:BHF-UCL	P	positive regulation of macrophage derived foam cell differentiation
GO:0009791	IEA:Ensembl	P	post-embryonic development
GO:0006898	TAS:Reactome	P	receptor-mediated endocytosis
GO:0045540	IEA:Ensembl	P	regulation of cholesterol biosynthetic process
GO:0009743	IEA:Ensembl	P	response to carbohydrate
GO:0032496	IEA:Ensembl	P	response to lipopolysaccharide
GO:0010269	IEA:Ensembl	P	response to selenium ion
GO:0009615	IEP:UniProtKB	P	response to virus
GO:0001523	TAS:Reactome	P	retinoid metabolic process
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0007283	IEA:Ensembl	P	spermatogenesis
GO:0030317	IEA:Ensembl	P	sperm motility
GO:0019433	IEA:Ensembl	P	triglyceride catabolic process
GO:0006642	IEA:Ensembl	P	triglyceride mobilization
GO:0034379	IC:BHF-UCL	P	very-low-density lipoprotein particle assembly

KEGG Pathway Links

KEGG Pathway ID	Description
hsa04975	Fat digestion and absorption
hsa04977	Vitamin digestion and absorption

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_164002	Scavenging by Class H Receptors