LMPD Database

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LMP001195

UniProt Annotations

Entry Information
Gene Nameretinol binding protein 4, plasma
Protein EntryRET4_HUMAN
UniProt IDP02753
SpeciesHuman
Comments
Comment typeDescription
DiseaseRetinal dystrophy, iris coloboma, and comedogenic acne syndrome (RDCCAS) [MIM
FunctionDelivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
InteractionO55245:TTR (xeno); NbExp=2; IntAct=EBI-2116134, EBI-7038226;
Mass SpectrometryMass=20162; Method=MALDI; Range=19-194; Evidence= ;
Mass SpectrometryMass=20534; Method=MALDI; Range=19-197; Evidence= ;
Mass SpectrometryMass=21063.46; Mass_error=1.88; Method=Electrospray; Range=17-199; Evidence= ;
Sequence CautionSequence=AAF69622.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the calycin superfamily. Lipocalin family.
Subcellular LocationSecreted.
Web ResourceName=Mutations of the RBP4 gene; Note=Retina International's Scientific Newsletter; URL="http://www.retina-international.org/files/sci-news/rlbp4mut.htm";
Web ResourceName=Wikipedia; Note=Retinol-binding protein 4 entry; URL="http://en.wikipedia.org/wiki/Retinol_binding_protein_4";