LMPD Database

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LMP001450

UniProt Annotations

Entry Information
Gene Namehydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
Protein EntryECHB_MOUSE
UniProt IDQ99JY0
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.
PathwayLipid metabolism; fatty acid beta-oxidation.
PtmAcetylation of Lys-202 is observed in liver mitochondria from fasted mice but not from fed mice. {ECO:0000269|PubMed:23576753}.
SimilarityBelongs to the thiolase family. {ECO:0000305}.
Subcellular LocationMitochondrion {ECO:0000250}. Mitochondrion inner membrane {ECO:0000250}. Mitochondrion outer membrane {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
SubunitOctamer of 4 alpha (HADHA) and 4 beta (HADHB) subunits. Interacts with RSAD2/viperin. {ECO:0000250}.