LMPD Database

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LMP001519

Gene Information

Entrez Gene ID3141
Gene Nameholocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
Gene SymbolHLCS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0000785 IDA:UniProtKBCchromatin
GO:0005737 IDA:HPACcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0005739 IEA:UniProtKB-KWCmitochondrion
GO:0005652 IDA:UniProtKBCnuclear lamina
GO:0016363 IDA:UniProtKBCnuclear matrix
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004077 IEA:UniProtKB-ECFbiotin-[acetyl-CoA-carboxylase] ligase activity
GO:0009374 IDA:UniProtKBFbiotin binding
GO:0004078 IEA:UniProtKB-ECFbiotin-[methylcrotonoyl-CoA-carboxylase] ligase activity
GO:0004079 IEA:UniProtKB-ECFbiotin-[methylmalonyl-CoA-carboxytransferase] ligase activity
GO:0004080 IDA:UniProtKBFbiotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity
GO:0018271 IDA:UniProtKBFbiotin-protein ligase activity
GO:0019899 IPI:UniProtKBFenzyme binding
GO:0006768 TAS:ReactomePbiotin metabolic process
GO:0008283 IMP:UniProtKBPcell proliferation
GO:0071110 IDA:UniProtKBPhistone biotinylation
GO:0016570 IDA:UniProtKBPhistone modification
GO:0009305 IDA:UniProtKBPprotein biotinylation
GO:0070781 IDA:UniProtKBPresponse to biotin
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006766 TAS:ReactomePvitamin metabolic process
GO:0006767 TAS:ReactomePwater-soluble vitamin metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00780Biotin metabolism
hsa01100Metabolic pathways
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY0-1264biotin-carboxyl carrier protein assembly
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_11153Biotin transport and metabolism