LMPD Database

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LMP001557

UniProt Annotations

Entry Information
Gene Namefatty acid binding protein 2, intestinal
Protein EntryFABPI_MOUSE
UniProt IDP55050
SpeciesMouse
Comments
Comment typeDescription
DomainForms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. {ECO:0000250}.
FunctionFABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. {ECO:0000269|PubMed:11023988}.
SimilarityBelongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. {ECO:0000305}.
Subcellular LocationCytoplasm.
Tissue SpecificityExpressed in the small intestine. Highest expression levels in the proximal ileum. {ECO:0000269|PubMed:9277406}.