LMPD Database

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LMP001599

UniProt Annotations

Entry Information
Gene Namealdehyde dehydrogenase family 1, subfamily A2
Protein EntryAL1A2_MOUSE
UniProt IDQ62148
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityRetinal + NAD(+) + H(2)O = retinoate + NADH.
FunctionRecognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently (By similarity). {ECO:0000250}.
PathwayCofactor metabolism; retinol metabolism.
Sequence CautionSequence=BAC37332.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAA67666.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the aldehyde dehydrogenase family. {ECO:0000305}.
Subcellular LocationCytoplasm.
SubunitHomotetramer. {ECO:0000250}.