LMPD Database

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LMP001799

UniProt Annotations

Entry Information
Gene Nameacyl-Coenzyme A oxidase 2, branched chain
Protein EntryACOX2_MOUSE
UniProt IDQ9QXD1
SpeciesMouse
Comments
Comment typeDescription
Catalytic Activity(25R)-3-alpha,7-alpha,12-alpha-trihydroxy-5- beta-cholestan-26-oyl-CoA + H(2)O + acceptor = (24R,25R)-3- alpha,7-alpha,12-alpha,24-tetrahydroxy-5-beta-cholestan-26-oyl-CoA + reduced acceptor.
CofactorName=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
FunctionOxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycoprostanic acids. {ECO:0000250}.
PtmAcetylation of Lys-667 is observed in liver mitochondria from fasted mice but not from fed mice.
SimilarityBelongs to the acyl-CoA oxidase family. {ECO:0000305}.
Subcellular LocationPeroxisome {ECO:0000250}.