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LMPD Database

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LMP001868

Gene Information

Entrez Gene ID	8821
Gene Name	inositol polyphosphate-4-phosphatase, type II, 105kDa
Gene Symbol	INPP4B
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005829	TAS:Reactome	C	cytosol
GO:0005794	IEA:Ensembl	C	Golgi apparatus
GO:0008289	IEA:Ensembl	F	lipid binding
GO:0016316	TAS:ProtInc	F	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity
GO:0034597	IEA:UniProtKB-EC	F	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
GO:0034594	IEA:Ensembl	F	phosphatidylinositol trisphosphate phosphatase activity
GO:0006874	IEA:Ensembl	P	cellular calcium ion homeostasis
GO:0043647	TAS:Reactome	P	inositol phosphate metabolic process
GO:0045671	IEA:Ensembl	P	negative regulation of osteoclast differentiation
GO:0006661	TAS:Reactome	P	phosphatidylinositol biosynthetic process
GO:0006644	TAS:Reactome	P	phospholipid metabolic process
GO:0046850	IEA:Ensembl	P	regulation of bone remodeling
GO:0046822	IEA:Ensembl	P	regulation of nucleocytoplasmic transport
GO:0051896	IEA:Ensembl	P	regulation of protein kinase B signaling
GO:0007165	TAS:ProtInc	P	signal transduction
GO:0044281	TAS:Reactome	P	small molecule metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_150352	Synthesis of IP2, IP, and Ins in the cytosol
REACT_120756	Synthesis of PIPs at the early endosome membrane
REACT_121025	Synthesis of PIPs at the plasma membrane