LMPD Database

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LMP002143

Gene Information

Entrez Gene ID10858
Gene Namecytochrome P450, family 46, subfamily A, polypeptide 1
Gene SymbolCYP46A1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 TAS:ProtIncCendoplasmic reticulum
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0033781 IDA:UniProtKBFcholesterol 24-hydroxylase activity
GO:0020037 IDA:UniProtKBFheme binding
GO:0005506 IEA:InterProFiron ion binding
GO:0008395 TAS:ProtIncFsteroid hydroxylase activity
GO:0006699 TAS:ReactomePbile acid biosynthetic process
GO:0008206 TAS:ReactomePbile acid metabolic process
GO:0006707 IDA:UniProtKBPcholesterol catabolic process
GO:0007399 TAS:ProtIncPnervous system development
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0016125 TAS:ReactomePsterol metabolic process
GO:0006805 IDA:UniProtKBPxenobiotic metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa00120Primary bile acid biosynthesis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_11053Synthesis of bile acids and bile salts via 24-hydroxycholesterol