LMPD Database

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LMP002367

Gene Information

Entrez Gene ID51763
Gene Nameinositol polyphosphate-5-phosphatase K
Gene SymbolINPP5K
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 ISS:UniProtKBCcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0005783 IDA:UniProtKBCendoplasmic reticulum
GO:0016020 IDA:UniProtKBCmembrane
GO:0043005 IDA:UniProtKBCneuron projection
GO:0005634 IDA:UniProtKBCnucleus
GO:0048471 IDA:UniProtKBCperinuclear region of cytoplasm
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0001726 IDA:MGICruffle
GO:0032587 IDA:UniProtKBCruffle membrane
GO:0005802 IDA:UniProtKBCtrans-Golgi network
GO:0052659 IEA:UniProtKB-ECFinositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
GO:0052658 IEA:UniProtKB-ECFinositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0016312 IDA:MGIFinositol bisphosphate phosphatase activity
GO:0004445 IEA:UniProtKB-ECFinositol-polyphosphate 5-phosphatase activity
GO:0046030 IDA:MGIFinositol trisphosphate phosphatase activity
GO:0042577 NAS:UniProtKBFlipid phosphatase activity
GO:0034485 IDA:UniProtKBFphosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
GO:0034595 IMP:UniProtKBFphosphatidylinositol phosphate 5-phosphatase activity
GO:0034594 IDA:UniProtKBFphosphatidylinositol trisphosphate phosphatase activity
GO:0005000 ISS:UniProtKBFvasopressin receptor activity
GO:0030036 NAS:UniProtKBPactin cytoskeleton organization
GO:0071320 ISS:UniProtKBPcellular response to cAMP
GO:0071364 IDA:UniProtKBPcellular response to epidermal growth factor stimulus
GO:0032870 ISS:UniProtKBPcellular response to hormone stimulus
GO:0032869 IDA:UniProtKBPcellular response to insulin stimulus
GO:0071356 IDA:UniProtKBPcellular response to tumor necrosis factor
GO:0016311 IDA:GOCPdephosphorylation
GO:0042593 ISS:UniProtKBPglucose homeostasis
GO:0007186 ISS:UniProtKBPG-protein coupled receptor signaling pathway
GO:0046855 IDA:MGIPinositol phosphate dephosphorylation
GO:0001701 IEA:EnsemblPin utero embryonic development
GO:0043922 IDA:UniProtKBPnegative regulation by host of viral transcription
GO:0051926 IDA:UniProtKBPnegative regulation of calcium ion transport
GO:0035305 ISS:UniProtKBPnegative regulation of dephosphorylation
GO:0010829 IDA:UniProtKBPnegative regulation of glucose transport
GO:0045719 IDA:UniProtKBPnegative regulation of glycogen biosynthetic process
GO:2000466 ISS:UniProtKBPnegative regulation of glycogen (starch) synthase activity
GO:0046627 IDA:UniProtKBPnegative regulation of insulin receptor signaling pathway
GO:0043407 IDA:UniProtKBPnegative regulation of MAP kinase activity
GO:0033137 IDA:UniProtKBPnegative regulation of peptidyl-serine phosphorylation
GO:0010801 IDA:UniProtKBPnegative regulation of peptidyl-threonine phosphorylation
GO:0006469 IDA:UniProtKBPnegative regulation of protein kinase activity
GO:0051898 IDA:UniProtKBPnegative regulation of protein kinase B signaling
GO:0001933 ISS:UniProtKBPnegative regulation of protein phosphorylation
GO:0090315 IDA:UniProtKBPnegative regulation of protein targeting to membrane
GO:0045869 IDA:UniProtKBPnegative regulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:0051497 IDA:UniProtKBPnegative regulation of stress fiber assembly
GO:0045892 ISS:UniProtKBPnegative regulation of transcription, DNA-templated
GO:0006661 TAS:ReactomePphosphatidylinositol biosynthetic process
GO:0046856 IDA:UniProtKBPphosphatidylinositol dephosphorylation
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:2001153 ISS:UniProtKBPpositive regulation of renal water transport
GO:0045893 ISS:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0035810 ISS:UniProtKBPpositive regulation of urine volume
GO:0072661 ISS:UniProtKBPprotein targeting to plasma membrane
GO:0005979 ISS:UniProtKBPregulation of glycogen biosynthetic process
GO:0097178 IDA:UniProtKBPruffle assembly
GO:0044281 TAS:ReactomePsmall molecule metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04910Insulin signaling pathway
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY-63621D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_121025Synthesis of PIPs at the plasma membrane