LMPD Database

LMP002384

Gene Information

Entrez Gene ID	5538
Gene Name	palmitoyl-protein thioesterase 1
Gene Symbol	PPT1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0030424	IDA:UniProtKB	C	axon
GO:0005829	ISS:UniProtKB	C	cytosol
GO:0030425	IEA:Ensembl	C	dendrite
GO:0005576	IDA:UniProtKB	C	extracellular region
GO:0005615	IEA:Ensembl	C	extracellular space
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005794	IDA:UniProtKB	C	Golgi apparatus
GO:0005764	IDA:UniProtKB	C	lysosome
GO:0016020	IDA:UniProtKB	C	membrane
GO:0045121	IDA:UniProtKB	C	membrane raft
GO:0043025	IEA:Ensembl	C	neuronal cell body
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0008021	IDA:UniProtKB	C	synaptic vesicle
GO:0016290	IDA:UniProtKB	F	palmitoyl-CoA hydrolase activity
GO:0008474	IDA:UniProtKB	F	palmitoyl-(protein) hydrolase activity
GO:0008344	IEA:Ensembl	P	adult locomotory behavior
GO:0008306	IEA:Ensembl	P	associative learning
GO:0007420	IMP:UniProtKB	P	brain development
GO:0008219	IEA:UniProtKB-KW	P	cell death
GO:0044257	IEA:Ensembl	P	cellular protein catabolic process
GO:0051186	IMP:UniProtKB	P	cofactor metabolic process
GO:0051181	IMP:UniProtKB	P	cofactor transport
GO:0007625	IEA:Ensembl	P	grooming behavior
GO:0016042	IDA:UniProtKB	P	lipid catabolic process
GO:0007042	IMP:UniProtKB	P	lysosomal lumen acidification
GO:0031579	IMP:UniProtKB	P	membrane raft organization
GO:0043066	IDA:UniProtKB	P	negative regulation of apoptotic process
GO:0030308	IMP:UniProtKB	P	negative regulation of cell growth
GO:0043524	IMP:UniProtKB	P	negative regulation of neuron apoptotic process
GO:0007399	IMP:UniProtKB	P	nervous system development
GO:0048666	TAS:UniProtKB	P	neuron development
GO:0007269	IEA:Ensembl	P	neurotransmitter secretion
GO:0006907	IMP:MGI	P	pinocytosis
GO:0048549	IMP:UniProtKB	P	positive regulation of pinocytosis
GO:0048260	IMP:UniProtKB	P	positive regulation of receptor-mediated endocytosis
GO:0030163	NAS:UniProtKB	P	protein catabolic process
GO:0002084	IDA:UniProtKB	P	protein depalmitoylation
GO:0015031	IMP:UniProtKB	P	protein transport
GO:0006898	IMP:MGI	P	receptor-mediated endocytosis
GO:0032429	IEA:Ensembl	P	regulation of phospholipase A2 activity
GO:0050803	NAS:UniProtKB	P	regulation of synapse structure and activity
GO:0030149	TAS:UniProtKB	P	sphingolipid catabolic process
GO:0007601	IEA:UniProtKB-KW	P	visual perception

KEGG Pathway Links

KEGG Pathway ID	Description
hsa00062	Fatty acid elongation
hsa01212	Fatty acid metabolism
hsa04142	Lysosome
hsa01100	Metabolic pathways